What is the function of the thymus gland in the immune system?
The thymus gland, often overlooked in discussions about immunity, plays a critical role in developing and training T-cells, which are essential components of the adaptive immune system. Located in the upper chest behind the sternum, this small organ is most active during childhood and adolescence, where it produces and matures T-lymphocytes. These cells learn to distinguish between the body's own tissues and foreign pathogens, preventing autoimmune reactions while enabling targeted attacks on infections. As we age, the thymus gradually shrinks and becomes less active—a process called thymic involution—which contributes to the decline in immune function in older adults. Recent research highlights that the thymus's role extends beyond early life; it continues to support immune memory and response regulation, making it vital for long-term health. Understanding its function helps explain why immune deficiencies or autoimmune diseases can arise when thymic activity is impaired, emphasizing its importance in maintaining overall immune balance.
📖 Read the full article: Effect van de zwezerik op onze immuniteit lang onderschat: "Klein orgaantje speelt echt een belangrijke rol" - VRT